A 2021 Fox News interview featuring Sen. J.D. Vance, who smeared Vice President Kamala Harris as part of a group of “childless cat ladies,” has resurfaced, causing widespread anger now that he is the Republican vice presidential nominee.

In the interview, Vance criticized prominent Democrats, including Harris, Transportation Secretary Pete Buttigieg, and U.S. Rep. Alexandria Ocasio-Cortez, for not having biological children.

“We are effectively run in this country via the Democrats, via our corporate oligarchs, by a bunch of childless cat ladies who are miserable at their own lives and the choices that they’ve made and so they want to make the rest of the country miserable too,” Vance said. “How does it make any sense that we’ve turned our country over to people who don’t really have a direct stake in it?” he asked.

The interview began circulating widely after Hillary Clinton shared the clip on X, commenting, “What a normal, relatable guy who certainly doesn’t hate women having freedoms.” Vance did not immediately respond to a request for comment from ABC News.

Though Harris does not have biological children, she has two stepchildren, Cole and Ella Emhoff, who affectionately call her “Momala.” Kerstin Emhoff, second gentleman Doug Emhoff’s ex-wife and mother to Cole and Ella, has been a vocal supporter of Harris and defended her against attacks on her parental status.

“These are baseless attacks. For over 10 years, since Cole and Ella were teenagers, Kamala has been a co-parent with Doug and me,” she said. “She is loving, nurturing, fiercely protective, and always present. I love our blended family and am grateful to have her in it.”

Ella Emhoff shared her mother’s statement on Instagram, writing, “I love my three parents.” She added, “How can you be ‘childless’ when you have cutie pie kids like Cole and me?”

Buttigieg also responded to Vance’s comments in a CNN interview, emphasizing that Vance should not speak about other people’s children.

“The really sad thing is he said that after Chasten and I had been through a fairly heartbreaking setback in our adoption journey,” Buttigieg said. “He couldn’t have known that, but maybe that’s why you shouldn’t be talking about other people’s children. It’s not about his kids, my kids, or the vice president’s family. It’s about your family, people’s families, whose well-being will depend on whether we go into a future led by somebody like Kamala Harris, who is focused on expanding the prosperity, the freedom, the well-being of our families.”